Kinexa Biosensor | SPR Applications

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Our KinExA Biosensor equipment is reliable for characterization of molecular interactions and cells, which is essentially complementary to the Surface Plasmon Resonance (SPR) technology. KinExA Biosensor can accurately determine the binding elements of a combination of biomolecules at femto-molar level.

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What is Surface Plasmon Resonance (SPR)?

To define what Surface Plasmon Resonance (SPR) is, it mainly refers to the technology that is used for the characterization of molecular interactions and cells. It is highly involved in antibody characterization and affinity measurements. This technology is popular among the biotech industry for cell quantitative analysis and for analysing protein to protein interactions.

This technology and method is used across several industries and types of research applications such as: drugs discovery, food quality analysis, life science discovery, chemical sensor analysis, and more.

Our KinExA Biosensor equipment is one of the most popular equipment used to carry out this process.

Advantages of Surface Plasmon Resonance (SPR)

SPR Surface Plasmon Resonance advantages include: (1) Label-free detection, (2) real-time monitoring, (3) low volume sample analysis, (4) easy quantitative evaluation, (5) highly cost-effective, and (6) easy determination of kinetic rate constants.

What is KinExA?

To define what KinExA is, it mainly refers to the technology that is used for the characterization of molecular interactions and cells. It is highly involved in antibody characterization and affinity measurements. This technology is popular among the biotech industry for cell quantitative analysis and for analysing protein to protein interactions at tight level, namely sub-nano-molar and tighter.

This technology and method is used across several industries and types of research applications such as: drugs discovery, food quality analysis, life science discovery, chemical sensor analysis, and more.

Our KinExA Biosensor equipment is one of the most popular equipment used to carry out this process.

Advantages of KinExA

KinExA advantages include: (1) complementary to Surface Plasmon Resonance analysis to analyse sub-nanomolar and tighter binding pairs, (2) true solution phase measurement, namely in physiological state of binding pairs, (3) label free measurement, (4) full binding characterization of equilibrium constant and kinetic rate constant, KD, kon and koff (5) contract measurement services available.

Kinexa Biosensor | SPR Applications

Advantages of a Kinetic Exclusion Assay (KinExA)

  • Can measure cellularly expressed proteins.
  • Measurements can be made with unpurified materials. (e.g. serum, cell lysates, ascites fluid, supernatants, etc.)
  • Measures a wide range of binding constants.
  • Versatile assay formats.
  • Can identify non-standard binding interactions such as cooperativity and mixtures.
  • No risk of mass transport limitations or artifacts that may mask true binding constants.
  • Highly reproducible.